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Article

Position 156 influences the peptide repertoire and tapasin dependency of human leukocyte antigen B*44 allotypes.

Haematologica - 1 Jan 2012

Badrinath Soumya, Saunders Philippa, Huyton Trevor, Aufderbeck Susanne, Hiller Oliver, Blasczyk Rainer, Bade-Doeding Christina

Abstract excerpt

BACKGROUND: Polymorphic differences between donor and recipient human leukocyte antigen class I molecules can result in graft-versus-host disease due to distinct peptide presentation. As part of the peptide-loading complex, tapasin plays an important role in selecting peptides from the pool of potential ligands. Class I polymorphisms can significantly alter the tapasin-mediated interaction with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21993680
DOI: 10.3324/haematol.2011.046037
PMCID: PMC3248936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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