Article
The polymorphism at residue 156 determines the HLA-B*35 restricted peptide repertoire during HCMV infection.
Immunogenetics - 1 Nov 2018
Abels Wiebke C, Manandhar Trishna, Kunze-Schumacher Heike, Blasczyk Rainer, Bade-Döding Christina
Abstract excerpt
Peptide selection in infected cells is not fully understood yet, but several indications point to the fact that there are differences to uninfected cells, especially in productive HCMV infection, since HCMV evolved various strategies to disable the hosts immune system, including presentation of peptide-HLA complexes to immune effector cells. Therefore, peptide predictions for specific HLA alleles are limited in...
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