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Article

Modes of metabolic compensation during mitochondrial disease using the Drosophila model of ATP6 dysfunction.

PloS one - 1 Jan 2011

Celotto Alicia M, Chiu Wai Kan, Van Voorhies Wayne, Palladino Michael J

Abstract excerpt

Numerous mitochondrial DNA mutations cause mitochondrial encephalomyopathy: a collection of related diseases for which there exists no effective treatment. Mitochondrial encephalomyopathies are complex multisystem diseases that exhibit a relentless progression of severity, making them both difficult to treat and study. The pathogenic and compensatory metabolic changes that are associated with chronic...

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Identifiers

PMID: 21991365
DOI: 10.1371/journal.pone.0025823
PMCID: PMC3185040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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