Article

Accelerated physiology and increased energy expenditure in animals and humans with mitochondrial defects: A meta-analysis

2023-09-10

Abstract excerpt

Mitochondria are key energy transforming organelles in mammalian cells. However, how defects in oxidative phosphorylation (OxPhos) and other mitochondrial functions influence whole-body energy expenditure (EE) has not been rigorously studied. Cellular and organismal responses to OxPhos defects likely involve a combination of functional downregulation to conserve energy and compensatory upregulation of stress res...

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Literature Corpus work: c106135f-9071-523f-9b58-81032999af27
DOI: 10.1101/2023.09.09.556754

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