Article
Regulation of the C. elegans molt by pqn-47.
Developmental biology - 15 Dec 2011
Russel Sascha, Frand Alison R, Ruvkun Gary
Abstract excerpt
C. elegans molts at the end of each of its four larval stages but this cycle ceases at the reproductive adult stage. We have identified a regulator of molting, pqn-47. Null mutations in pqn-47 cause a developmental arrest at the first larval molt, showing that this gene activity is required to transit the molt. Mutants with weak alleles of pqn-47 complete the larval molts but fail to exit the molting cycle at the...
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