Article
A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting.
Development (Cambridge, England) - 1 Feb 1999
Yochem J, Tuck S, Greenwald I, Han M
Abstract excerpt
A genetic analysis of a gp330/megalin-related protein, LRP-1, has been undertaken in Caenorhabditis elegans. Consistent with megalin's being essential for development of mice, likely null mutations reveal that this large member of the low density lipoprotein receptor family is also essential for growth and development of this nematode. The mutations confer a striking defect, an inability to shed and degrade all...
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