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Article

C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting.

Developmental biology - 15 Feb 2015

Yochem John, Lažetić Vladimir, Bell Leslie, Chen Lihsia, Fay David

Abstract excerpt

Caenorhabditis elegans molting is a process during which the apical extracellular matrix of the epidermis, the cuticle, is remodeled through a process of degradation and re-synthesis. Using a genetic approach, we identified nekl-3 as essential for the completion of molting. NEKL-3 is highly similar to the mammalian NEK kinase family members NEK6 and NEK7. Animals homozygous for a hypomorphic mutation in nekl-3,...

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Source

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Identifiers

PMID: 25523392
DOI: 10.1016/j.ydbio.2014.12.008
PMCID: PMC4314388

Genes

NEK6
NEK7
NEK8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting.PMID 25523392Read ↗

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