Article
Characterization of filovirus protein-protein interactions in mammalian cells using bimolecular complementation.
The Journal of infectious diseases - 1 Nov 2011
Liu Yuliang, Stone Sasha, Harty Ronald N
Abstract excerpt
The virion protein 40 (VP40) and nucleoprotein (NP) of Ebola (EBOV) and Marburg viruses (MARV) play key roles during virion assembly and egress. The ability to detect interactions between VP40-VP40, VP40-NP, and NP-NP and follow these complexes as they traffic through mammalian cells would enhance our understanding of the molecular events leading to filovirus assembly and budding, and provide new insights into...
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