Article
Haptoglobin polymorphism is not associated with prostate cancer in blacks.
Clinica chimica acta; international journal of clinical chemistry - 18 Jan 2012
Mavondo Greanious A, Mangena Zivanai, Kasvosve Ishmael
Abstract excerpt
BACKGROUND: Prostate cancer (Pca) disease burden is highest among male blacks. Oxidative stress due to hemoglobin-related oxygen reactive species is a risk factor for cancer development. The polymorphic haptoglobin (Hp) protein inhibits hemoglobin-related oxidative stress. The antioxidant capacity of Hp is genetically determined. We studied the effect of Hp polymorphism on susceptibility to Pca. SUBJECTS AND...
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