Article
Haptoglobin polymorphism and prostate cancer mortality.
Scientific reports - 4 Aug 2020
Kaiser Melanie, Thurner Eva-Maria, Mangge Harald, Herrmann Markus, Semeraro Maria Donatella, Renner Wilfried, Langsenlehner Tanja
Abstract excerpt
Prostate cancer is a common malignancy in men worldwide and it is known that oxidative stress is a risk factor for cancer development. A common functional haptoglobin (Hp) polymorphism, originating from a duplication of a gene segment spanning over two exons, results in three distinct phenotypes with different anti-oxidative capacities: Hp1-1, Hp1-2, and Hp2-2. The aim of the study was to investigate the...
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