Article
Polymorphisms in oxidative stress-related genes are not associated with prostate cancer risk in heavy smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2007
Choi Ji-Yeob, Neuhouser Marian L, Barnett Matt, Hudson Matthew, Kristal Alan R, Thornquist Mark, King Irena B, Goodman Gary E, Ambrosone Christine B
Abstract excerpt
Oxidative stress, associated with aging and inflammation, is likely to play a role in the etiology of prostate cancer. We evaluated potential associations between gene variants that result in reduced neutralization of reactive oxygen species (ROS; MnSOD Ala-16Val, CAT -262 C>T, and GPX1 Pro200Leu) and prostate cancer risk among 724 men with incident prostate cancer who participated in the Carotene and Retinol...
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