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Article

Antibiotics-free stable polyhydroxyalkanoate (PHA) production from carbon dioxide by recombinant cyanobacteria.

Bioresource technology - 1 Dec 2011

Akiyama Hideo, Okuhata Hiroshi, Onizuka Takuo, Kanai Shozo, Hirano Masahiko, Tanaka Satoshi, Sasaki Ken, Miyasaka Hitoshi

Abstract excerpt

A practical antibiotics-free plasmid expression system in cyanobacteria was developed by using the complementation of cyanobacterial recA null mutation with the EscherichiacolirecA gene on the plasmid. This system was applied to the production of polyhydroxyalkanoate (PHA), a biodegradable plastic, and the transgenic cyanobacteria stably maintained the pha genes for PHA production in the antibiotics-free medium,...

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Identifiers

PMID: 21983412
DOI: 10.1016/j.biortech.2011.09.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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