Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intrinsic AhR function underlies cross-talk of dioxins with sex hormone signalings.

Biochemical and biophysical research communications - 13 Jun 2008

Ohtake Fumiaki, Baba Atsushi, Fujii-Kuriyama Yoshiaki, Kato Shigeaki

Abstract excerpt

The arylhydrocarbon receptor (AhR) mediates sex steroid hormone-related actions in both normal physiology and in dioxin toxicity. In addition to regulation of direct target genes, the ligand-activated AhR associates with estrogen or androgen receptors (ERalpha or AR) to regulate transcription as a functional unit. Given that endogenous and exogenous AhR-ligands are structurally diverse, it is unclear whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androgens
Share to Estrogen Receptor alpha
Share to Estrogens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ligands

Share to Proteasome Endopeptidase Complex

Share to Receptors, Androgen

Share to Receptors, Aryl Hydrocarbon

Share to Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 18358233
DOI: 10.1016/j.bbrc.2008.03.054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intrinsic AhR function underlies cross-talk of dioxins with sex hormone signalings.PMID 18358233Read ↗

Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction.Semantic proximity Read ↗

The transcription factor aryl hydrocarbon receptor nuclear translocator functions as an estrogen receptor beta-selective coactivator, and its recruitment to alternative pathways mediates antiestrogenic effects of dioxin.Semantic proximity Read ↗

The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value.Semantic proximity Read ↗

Dioxin toxicity in vivo results from an increase in the dioxin-independent transcriptional activity of the aryl hydrocarbon receptor.Semantic proximity Read ↗

Aryl hydrocarbon receptor (AHR): From selected human target genes and crosstalk with transcription factors to multiple AHR functionsSemantic proximity Read ↗

Gene-environment interactions in male reproductive health: special reference to the aryl hydrocarbon receptor signaling pathway.Semantic proximity Read ↗

[Clarification of molecular targets of dioxin toxicity].Semantic proximity Read ↗

Human and rodent aryl hydrocarbon receptor (AHR): from mediator of dioxin toxicity to physiologic AHR functions and therapeutic options.Semantic proximity Read ↗

Dynamic relationship between the aryl hydrocarbon receptor and long noncoding RNA balances cellular and toxicological responsesSemantic proximity Read ↗

Distinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor in estrogen-mediated signaling in human cancer cell lines.Semantic proximity Read ↗

Old Receptor, New Tricks—The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report from the 4th AHR Meeting, 29–31 August 2018 in Paris, FranceSemantic proximity Read ↗

The constitutively active Ah receptor (CA-Ahr) mouse as a potential model for dioxin exposure--effects in vital organs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.