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Article

The potential role of Aurora kinase inhibitors in haematological malignancies

8 Oct 2011

Abstract excerpt

Aurora kinases play an important role in the control of the cell cycle and have been implicated in tumourigenesis in a number of cancers. Among the haematological malignancies, overexpression of Aurora kinases has been reported in acute myeloid leukaemia, chronic myeloid leukaemia, acute lymphoblastic leukaemia, multiple myeloma, aggressive non-Hodgkin lymphoma and Hodgkin lymphoma. A large number of Aurora...

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PMID: 21980926
DOI: 10.1111/j.1365-2141.2011.08898.x

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