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Article

RAD59 and RAD1 cooperate in translocation formation by single-strand annealing in Saccharomyces cerevisiae.

Current genetics - 1 Feb 2010

Pannunzio Nicholas R, Manthey Glenn M, Bailis Adam M

Abstract excerpt

Studies in the budding yeast, Saccharomyces cerevisiae, have demonstrated that a substantial fraction of double-strand break repair following acute radiation exposure involves homologous recombination between repetitive genomic elements. We have previously described an assay in S. cerevisiae that allows us to model how repair of multiple breaks leads to the formation of chromosomal translocations by single-strand...

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Share to DNA Breaks, Double-Stranded
Share to DNA Repair
Share to Mutation, Missense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Rad51 Recombinase

Share to Recombination, Genetic

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Translocation, Genetic

Source

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Identifiers

PMID: 20012294
DOI: 10.1007/s00294-009-0282-6
PMCID: PMC2808509

Genes

RAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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