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Article

Transcobalamin 2 variant associated with poststroke homocysteine modifies recurrent stroke risk.

Neurology - 18 Oct 2011

Hsu F-C, Sides E G, Mychaleckyj J C, Worrall B B, Elias G A, Liu Y, Chen W-M, Coull B M, Toole J F, Rich S S, Furie K L, Sale M M

Abstract excerpt

OBJECTIVES: The Vitamin Intervention for Stroke Prevention trial found an association between baseline poststroke homocysteine (Hcy) and recurrent stroke. We investigated genes for enzymes and cofactors in the Hcy metabolic pathway for association with Hcy and determined whether associated single nucleotide polymorphisms (SNPs) influenced recurrent stroke risk. METHODS: Eighty-six SNPs in 9 candidate genes...

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Source

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Identifiers

PMID: 21975197
DOI: 10.1212/WNL.0b013e318233b1f9
PMCID: PMC3198974

Genes

TCN2
CBS
BHMT2
CTH
MTHFR
MTR
MTRR
TCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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