Article
Pharmacogenetic studies of change in cortisol on ecstasy (MDMA) consumption.
Journal of psychopharmacology (Oxford, England) - 1 Mar 2012
Wolff Kim, Tsapakis Evangelia M, Pariante Carmine M, Kerwin Robert W, Forsling Mary L, Aitchison Katherine J
Abstract excerpt
In this study we investigate the association of cytochrome P450 enzyme CYP2D6, catechol-O-methyl transferase (COMT, Val158Met) and serotonin transporter promoter (5-HTTLPR) genotypes on change in cortisol concentration following 3, 4-methylenedioxy-methamphetamine (MDMA, 'ecstasy') consumption. Forty-eight subjects (30 males, mean age 23 years), self-nominating regular clubbers provided 'in the field' pre- and...
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