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Article

Polymorphism of glutathione S-transferase M1 and T1 genes and susceptibility to psoriasis disease: A study from North India.

Indian journal of dermatology, venereology and leprology - 1 Jan 2000

Srivastava Daya Shankar Lal, Jain Vijay K, Verma Poonam, Yadav Jaya P

Abstract excerpt

BACKGROUND: Increased oxidative stress and resulting inflammation has been emphasized as a factor in the pathogenesis of many diseases including psoriasis. Glutathione S-transferases (GSTs) protect against oxidative stress, inflammation, and genotoxicity. Polymorphisms in the GST genes may lead to an imbalance in pro- and antioxidant systems resulting in the increased production of reactive oxygen species that...

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Source

Identifiers

PMID: 29067933
DOI: 10.4103/ijdvl.IJDVL_1128_16

Genes

GSTT1
GSTM1

Provenance

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