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Article

The GSTM1 null genotype confers an increased risk for solar keratosis development in an Australian Caucasian population.

The Journal of investigative dermatology - 1 Dec 2002

Carless Melanie A, Lea Rod A, Curran Joanne E, Appleyard Bridget, Gaffney Phil, Green Adele, Griffiths Lyn R

Abstract excerpt

Solar keratoses affect approximately 50% of Australian Caucasians aged over 40 y. Solar keratoses can undergo malignant transformation into squamous cell carcinoma followed by possible metastasis and are risk factors for basal cell carcinoma, melanoma, and squamous cell carcinoma. The glutathione-S-transferase genes play a part in detoxification of carcinogens and mutagens, including some produced by ultraviolet...

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Source

Identifiers

PMID: 12485442
DOI: 10.1046/j.1523-1747.2002.19646.x

Genes

GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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The GSTM1 null genotype confers an increased risk for solar keratosis development in an Australian Caucasian population.PMID 12485442Read ↗

The null allele of GSTM1 does not affect susceptibility to solar keratoses in the Australian white population.Semantic proximity Read ↗

Polymorphism of glutathione S-transferases M1 and T1: susceptibility to solar keratoses in an Italian population.Semantic proximity Read ↗

Polymorphisms of GSTM1 and GSTT1, sun exposure and the risk of melanoma: a case-control study.Semantic proximity Read ↗

Effect of GSTM1 polymorphism on risks of basal cell carcinoma and squamous cell carcinoma: a meta-analysis.Semantic proximity Read ↗

Glutathione S-transferase GSTM1 null genotype is not overrepresented in Australian patients with nevoid basal cell carcinoma syndrome or sporadic melanoma.Semantic proximity Read ↗

Glutathione S-Transferase Theta 1 / Mu 1 Null Genotype and Risk of Development of Actinic Keratosis in Pakistani Population.Semantic proximity Read ↗

Glutathione S-transferase M1 null genotype, household pesticides exposure and cutaneous melanoma.Semantic proximity Read ↗

Interaction of glutathione S-transferase M1 and T1 genotypes and malignant melanoma.Semantic proximity Read ↗

Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumours.Semantic proximity Read ↗

Polymorphisms in glutathione S-transferases are associated with altered risk of nonmelanoma skin cancer in renal transplant recipients: a preliminary analysis.Semantic proximity Read ↗

Genetic analysis of genes GSTP1, PTEN, and TP53 SNPs in non-melanoma skin cancer patients.Semantic proximity Read ↗

Glutathione S-transferase M1 and T1 null genotypes as risk factors for oral leukoplakia in ethnic Indian betel quid/tobacco chewers.Semantic proximity Read ↗

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