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Article

Influence of GSTT1 and GSTM1 genotypes on sunburn sensitivity.

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice - 1 Jan 2002

Kerb Reinhold, Brockmoller Jürgen, Schlagenhaufer Robert, Sprenger Raimund, Roots Ivar, Brinkmann Ulrich

Abstract excerpt

BACKGROUND: Exposure to sunlight may cause sunburn, skin cancer or phototoxic reactions to certain drugs such as Hypericum extract. All these are ultraviolet B (UVB)-mediated reactions which may be modulated by individual genetic susceptibility. UVB exposure results in oxidative stress. Many products of oxidative stress are detoxified by glutathione-S-transferases mu 1 (GSTM1) and theta 1 (GSTT1). Deletion...

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Source

Identifiers

PMID: 12083949
DOI: 10.2165/00129785-200202020-00007

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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