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Article

Genetic variants of TSLP and asthma in an admixed urban population.

PloS one - 1 Jan 2011

Liu Mengling, Rogers Linda, Cheng Qinyi, Shao Yongzhao, Fernandez-Beros Maria Elena, Hirschhorn Joel N, Lyon Helen N, Gajdos Zofia K Z, Vedantam Sailaja, Gregersen Peter, Seldin Michael F, Bleck Bertram, Ramasamy Adaikalavan, Hartikainen Anna-Liisa, Jarvelin Marjo-Riitta, Kuokkanen Mikko, Laitinen Tarja, Eriksson Johan, Lehtimäki Terho, Raitakari Olli T, Reibman Joan

Abstract excerpt

BACKGROUND: Thymic stromal lymphopoietin (TSLP), an IL7-like cytokine produced by bronchial epithelial cells is upregulated in asthma and induces dendritic cell maturation supporting a Th2 response. Environmental pollutants, including tobacco smoke and diesel exhaust particles upregulate TSLP sug...

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Source

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Identifiers

PMID: 21966427
DOI: 10.1371/journal.pone.0025099
PMCID: PMC3178593

Genes

TSLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21966427-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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