Article
Traffic, asthma and genetics: combining international birth cohort data to examine genetics as a mediator of traffic-related air pollution's impact on childhood asthma.
European journal of epidemiology - 1 Jul 2013
MacIntyre Elaina A, Carlsten Christopher, MacNutt Meaghan, Fuertes Elaine, Melén Eric, Tiesler Carla M T, Gehring Ulrike, Krämer Ursula, Klümper Claudia, Kerkhof Marjan, Chan-Yeung Moira, Kozyrskyj Anita L, Berdel Dietrich, Bauer Carl Peter, Herbarth Olf, Bauer Mario, Schaaf Beate, Koletzko Sibylle, Pershagen Goran, Brunekreef Bert, Heinrich Joachim, Brauer Michael
Abstract excerpt
Associations between traffic-related air pollution and incident childhood asthma can be strengthened by analysis of gene-environment interactions, but studies have typically been limited by lack of study power. We combined data from six birth cohorts on: asthma, eczema and allergic rhinitis to 7/8 years, and candidate genes. Individual-level assessment of traffic-related air pollution exposure was estimated using...
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