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Article

Genomic instability in blood cells from murine model of mucopolysaccharidosis type I.

Journal of molecular histology - 1 Dec 2011

Noguti Juliana, Pereira Vanessa Gonçalves, Martins Ana Maria, D'Almeida Vânia, Ribeiro Daniel Araki

Abstract excerpt

Mucopolysaccharidosis type I (MPS I) is caused by a deficiency of alfa-iduronidase (IDUA), which leads to intralysosomal accumulation of glycosaminoglycans. Some studies have revealed that oxidative stress plays an important role in MPS I. However, the mechanisms by which these alterations occur are still not fully understood. The aim of this study was to analyze genomic instability in blood cells from murine...

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Source

Identifiers

PMID: 21965007
DOI: 10.1007/s10735-011-9361-3

Genes

IDUA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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