Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic instability in long-term culture of human adipose-derived mesenchymal stromal cells

1 Jan 2023

Abstract excerpt

Mesenchymal stromal/stem cells stem (MSC) have been widely studied due to their great potential for application in tissue engineering and regenerative and translational medicine. In MSC-based therapy for human diseases, cell proliferation is required to obtain a large and adequate number of cells to ensure therapeutic efficacy. During in vitro culture, cells are under an artificial environment and manipulative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37493771
DOI: 10.1590/1414-431x2023e12713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic instability in long-term culture of human adipose-derived mesenchymal stromal cellsPMID 37493771Read ↗

Ensuring Safety in Stem Cell Therapies: A Review of Tumorigenic Risks and Mitigation StrategiesSemantic proximity Read ↗

Human Adipose Stromal Cells (ASC) for the Regeneration of Injured Cartilage Display Genetic Stability after In Vitro Culture ExpansionSemantic proximity Read ↗

Stress and stem cells: adult Muse cells tolerate extensive genotoxic stimuli better than mesenchymal stromal cellsSemantic proximity Read ↗

Adipose tissue-derived stem cells from humans and mice differ in proliferative capacity and genome stability in long-term cultures.Semantic proximity Read ↗

Hypoxia Differentially Modulates the Genomic Stability of Clinical-Grade ADSCs and BM-MSCs in Long-Term CultureSemantic proximity Read ↗

Concise Review: Genomic Instability in Human Stem Cells: Current Status and Future ChallengesSemantic proximity Read ↗

Human mesenchymal stem cells as a novel platform for simultaneous evaluation of cytotoxicity and genotoxicity of pharmaceuticalsSemantic proximity Read ↗

Comparison of senescence phenotype of short- and long- term cultured rat mesenchymal stem cells in vitro.Semantic proximity Read ↗

Chemotherapy-induced genotoxic damage to bone marrow cells: long-term implicationsSemantic proximity Read ↗

Biosafety and Bioefficacy Assessment of Human Mesenchymal Stem Cells: What do we Know so Far?Semantic proximity Read ↗

Human mesenchymal stem cells with enhanced telomerase activity acquire resistance against oxidative stress-induced genomic damageSemantic proximity Read ↗

Long-term cultured mesenchymal stem cells frequently develop genomic mutations but do not undergo malignant transformation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.