Article
Absence of superoxide dismutase activity causes nuclear DNA fragmentation during the aging process.
Biochemical and biophysical research communications - 7 Feb 2014
Muid Khandaker Ashfaqul, Karakaya Hüseyin Çaglar, Koc Ahmet
Abstract excerpt
Superoxide dismutases (SOD) serve as an important antioxidant defense mechanism in aerobic organisms, and deletion of these genes shortens the replicative life span in the budding yeast Saccharomyces cerevisiae. Even though involvement of superoxide dismutase enzymes in ROS scavenging and the aging process has been studied extensively in different organisms, analyses of DNA damages has not been performed for...
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