Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest.

doi:10.1016/j.ydbio.2010.04.023

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Article

Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest.

Developmental biology - 1 Aug 2010

Curran Kevin, Lister James A, Kunkel Gary R, Prendergast Andrew, Parichy David M, Raible David W

Abstract excerpt

Pigment cells of the zebrafish, Danio rerio, offer an exceptionally tractable system for studying the genetic and cellular bases of cell fate decisions. In the zebrafish, neural crest cells generate three types of pigment cells during embryogenesis: yellow xanthophores, iridescent iridophores and black melanophores. In this study, we present evidence for a model whereby melanophores and iridophores descend from a...

Topics

Animals
Animals, Genetically Modified
Cell Lineage
Forkhead Transcription Factors
Gene Expression Regulation, Developmental
Melanocytes
Microphthalmia-Associated Transcription Factor
Microscopy, Fluorescence
Models, Biological
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neural Crest

Phylogeny

Pigmentation

Zebrafish

Zebrafish Proteins

Source

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Identifiers

PMID: 20460180
DOI: 10.1016/j.ydbio.2010.04.023
PMCID: PMC2909359

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