Article
Zebrafish mdk2, a novel secreted midkine, participates in posterior neurogenesis.
Developmental biology - 1 Jan 2001
Winkler C, Moon R T
Abstract excerpt
Patterning the neural plate in vertebrates depends on complex interactions between a variety of secreted growth factors. Here we describe a novel secreted factor in zebrafish, named mdk2, related to the midkine family of heparin-binding growth factors that is involved in posterior neural development. mdk2 is expressed shortly after the onset of gastrulation in the presumptive neural plate cells of the epiblast,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.