Article
Long-range massively parallel mate pair sequencing detects distinct mutations and similar patterns of structural mutability in two breast cancer cell lines.
Cancer genetics - 1 Aug 2011
Hampton Oliver A, Koriabine Maxim, Miller Christopher A, Coarfa Cristian, Li Jian, Den Hollander Petra, Schoenherr Caroline, Carbone Lucia, Nefedov Mikhail, Ten Hallers Boudewijn F H, Lee Adrian V, De Jong Pieter J, Milosavljevic Aleksandar
Abstract excerpt
Cancer genomes frequently undergo genomic instability resulting in accumulation of chromosomal rearrangement. To date, one of the main challenges has been to confidently and accurately identify these rearrangements by using short-read massively parallel sequencing. We were able to improve cancer...
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