Article
Alveolar mast cells shift to an FcεRI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology.
Allergy - 1 Dec 2011
Andersson C K, Tufvesson E, Aronsson D, Bergqvist A, Mori M, Bjermer L, Erjefält J S
Abstract excerpt
BACKGROUND: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild allergic asthma or...
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