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Article

Mast cell research.

Chemical immunology and allergy - 1 Jan 2014

Saito Hirohisa

Abstract excerpt

The role of mast cells in allergy remained unrevealed until the observation that they contained histamine in 1953, and then the discovery of immunoglobulin E (IgE) in 1966, nearly a century after Ehrlich's first publication. After the discovery of IgE, myeloma-derived IgE from Peter Shackford, who made a great contribution to mankind by providing 40 liters of plasma in the year prior to his death, was distributed...

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PMID: 24925397
DOI: 10.1159/000358733

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