Article
Asthma phenotypes and IgE responses.
The European respiratory journal - 1 Jan 2016
Froidure Antoine, Mouthuy Jonathan, Durham Stephen R, Chanez Pascal, Sibille Yves, Pilette Charles
Abstract excerpt
The discovery of IgE represented a major breakthrough in allergy and asthma research, whereas the clinical interest given to IgE in asthma has been blurred until the arrival of anti-IgE biotherapy. Novel facets of the complex link between IgE and asthma have been highlighted by the effect of this treatment and by basic research. In parallel, asthma phenotyping recently evolved to the concept of endotypes, relying...
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