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Article

The central role of FcεRI in allergy

1 Mar 2003

Abstract excerpt

The high-affinity receptor for immunoglobulin E (IgE), FcepsilonRI, plays a central role in the initiation and control of atopic allergic inflammation. On mast cells and basophils, the function of the receptor is well known and constitutes cellular degranulation and the release of various mediators. FcepsilonRI on antigen-presenting cells (APCs), however, does not lead to degranulation of preformed granula, but...

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Share to Allergic Rhinitis and Sensitization
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PMID: 12653710
DOI: 10.1046/j.1365-2230.2003.01209.x

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