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Article

The genetics of the human APOE polymorphism.

Rejuvenation research - 1 Oct 2011

Seripa Davide, D'Onofrio Grazia, Panza Francesco, Cascavilla Leandro, Masullo Carlo, Pilotto Alberto

Abstract excerpt

Abstract The genetic origin of the three common variants of the human apolipoprotein E (apoE) protein, known as E2, E3 and E4, was understood in 1981, and since the mid 1980s these are probably the most-studied protein variants in human races. They have been related to a number of age-related diseases, including Alzheimer disease, as well as to healthy aging and longevity. The gene variants underlying these...

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Source

Identifiers

PMID: 21958003
DOI: 10.1089/rej.2011.1169

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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