Article
The -1123G>C variant of PTPN22 gene promoter is associated with latent autoimmune diabetes in adult Chinese Hans.
Cell biochemistry and biophysics - 1 Mar 2012
Liu Fang, Liu Jiang, Zheng Tai-shan, Li Qing, Wang Chen, Pan Xiao-ping, Lu Huijuan, Zhao Yu-wu
Abstract excerpt
The protein tyrosine phosphatase non-receptor 22 (PTPN22) gene encodes for lymphoid protein tyrosine phosphatase. Recent studies demonstrated the association between the +1858T, -1123G>C variants of PTPN22 gene and type 1 diabetes mellitus in Caucasian and Japanese populations. This study examined the relationship between the polymorphism of PTPN22 gene and latent autoimmune 1 diabetes in adults (LADA) in Chinese...
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