Properties of case/pseudocontrol analysis for genetic association studies: Effects of recombination, ascertainment, and multiple affected offspring.

doi:10.1002/gepi.10306

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Article

Properties of case/pseudocontrol analysis for genetic association studies: Effects of recombination, ascertainment, and multiple affected offspring.

Genetic epidemiology - 1 Apr 2004

Cordell Heather J

Abstract excerpt

The case/pseudocontrol approach is a general framework for family-based association analysis, incorporating several previously proposed methods such as the transmission/disequilibrium test and log-linear modelling of parent-of-origin effects. In this report, I examine the properties of methods ba...

Topics

Algorithms
Computer Simulation
Female
Genetic Linkage
Genetic Markers
Genotype
Haplotypes
Humans
Linear Models
Linkage Disequilibrium
Logistic Models
Male
Models, Genetic
Recombination, Genetic

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