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Article

A novel nickel responsive MerR-like regulator, NimR, from Haemophilus influenzae.

Metallomics : integrated biometal science - 1 Oct 2011

Kidd Stephen P, Djoko Karrera Y, Ng JiaQi, Argente M Pilar, Jennings Michael P, McEwan Alastair G

Abstract excerpt

We have identified a novel regulator from the MerR family of transcription factors in the bacterial pathogen Haemophilus influenzae (HI1623; nickel-associated merR-like Regulator--NimR). NimR regulates the expression of a Ni(2+) uptake transporter (NikKLMQO). The promoters for nimR and the nik operon are divergent and overlapping and NimR binds at a site between the promoter elements for nikKLMQO. Expression of...

Topics

Bacterial Proteins
Base Sequence
Gene Expression Regulation, Bacterial
Haemophilus influenzae
Membrane Transport Proteins
Molecular Sequence Data
Mutation
Nickel
Promoter Regions, Genetic
Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Urease

Source

Identifiers

PMID: 21952667
DOI: 10.1039/c1mt00127b

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