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Article

Defining the regulatory mechanism of NikR, a nickel-responsive transcriptional regulator, in Brucella abortus.

Microbiology (Reading, England) - 1 Oct 2018

Budnick James A, Prado-Sanchez Evymarie, Caswell Clayton C

Abstract excerpt

Metals are essential micronutrients for virtually all forms of life, but metal acquisition is a double-edged sword, because high concentrations of divalent cations can be toxic to the cell. Therefore, the genes involved in metal acquisition, storage and efflux are tightly regulated. The present study characterizes a nickel-responsive transcriptional regulator in the intracellular mammalian pathogen, Brucella...

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Identifiers

PMID: 30062985
DOI: 10.1099/mic.0.000702
PMCID: PMC6600342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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