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Article

A shift of the TOR adaptor from Rictor towards Raptor by semaphorin in C. elegans.

Nature communications - 27 Sept 2011

Nukazuka Akira, Tamaki Shusaku, Matsumoto Kunihiro, Oda Yoichi, Fujisawa Hajime, Takagi Shin

Abstract excerpt

The target of rapamycin (TOR), a central regulator for cell growth and metabolism, resides in the two functionally distinct complexes TORC1 and TORC2, which are defined by their adaptors Raptor and Rictor, respectively. How the formation of the two TORCs is orchestrated remains unclear. Here we show the control of TOR partnering by semaphorin-plexin signalling in Caenorhabditis elegans. In semaphorin and plexin...

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PMID: 21952218
DOI: 10.1038/ncomms1495
PMCID: PMC3195255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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