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Article

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans.

Genes & development - 15 Feb 2009

Soukas Alexander A, Kane Elizabeth A, Carr Christopher E, Melo Justine A, Ruvkun Gary

Abstract excerpt

Rictor is a component of the target of rapamycin complex 2 (TORC2). While TORC2 has been implicated in insulin and other growth factor signaling pathways, the key inputs and outputs of this kinase complex remain unknown. We identified mutations in the Caenorhabditis elegans homolog of rictor in a forward genetic screen for increased body fat. Despite high body fat, rictor mutants are developmentally delayed,...

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Identifiers

PMID: 19240135
DOI: 10.1101/gad.1775409
PMCID: PMC2648650

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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