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Article

Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1.

PLoS biology - 3 Mar 2009

Jones Kevin T, Greer Elisabeth R, Pearce David, Ashrafi Kaveh

Abstract excerpt

The target of rapamycin (TOR) kinase coordinately regulates fundamental metabolic and cellular processes to support growth, proliferation, survival, and differentiation, and consequently it has been proposed as a therapeutic target for the treatment of cancer, metabolic disease, and aging. The TO...

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Identifiers

PMID: 19260765
DOI: 10.1371/journal.pbio.1000060
PMCID: PMC2650726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19260765-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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