Article
Rictor/TORC2 mediates gut-to-brain signaling in the regulation of phenotypic plasticity in C. elegans.
PLoS genetics - 1 Feb 2018
O'Donnell Michael P, Chao Pin-Hao, Kammenga Jan E, Sengupta Piali
Abstract excerpt
Animals integrate external cues with information about internal conditions such as metabolic state to execute the appropriate behavioral and developmental decisions. Information about food quality and quantity is assessed by the intestine and transmitted to modulate neuronal functions via mechanisms that are not fully understood. The conserved Target of Rapamycin complex 2 (TORC2) controls multiple processes in...
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