Article
Lack of association of vitamin D receptor gene 3'-haplotypes with psoriasis in Croatian patients.
The Journal of dermatology - 1 Jan 2012
Rucevic Ivana, Stefanic Mario, Tokic Stana, Vuksic Melita, Glavas-Obrovac Ljubica, Barisic-Drusko Vladimira
Abstract excerpt
Cis-acting regulatory variants in biologically relevant pathways and target tissues are a common source of phenotypic variations and individual disease susceptibility. In the skin, vitamin D receptor (VDR) is a master regulator of epidermal barrier function, inflammation, stem cell proliferation and microbial defense; therefore, we tested whether VDR 3'-regulatory haplotypes, a portion of which affect VDR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
