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Article

A-1012G promoter polymorphism of vitamin D receptor gene is associated with psoriasis risk and lower allele-specific expression.

DNA and cell biology - 1 Feb 2014

Richetta Antonio Giovanni, Silvestri Valentina, Giancristoforo Simona, Rizzolo Piera, D'Epiro Sara, Graziano Veronica, Mattozzi Carlo, Navazio Anna Sara, Campoli Marco, D'Amico Cristina, Scarnò Marco, Calvieri Stefano, Ottini Laura

Abstract excerpt

Psoriasis is caused by a combination of genetic, immunologic, and environmental factors. The vitamin D receptor (VDR) is involved in antiproliferative and prodifferentiation pathways in keratinocytes and exerts immunosuppressive effects. We aimed to investigate possible associations between VDR polymorphisms and psoriasis susceptibility and to evaluate functional effects of potential psoriasis-associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Share to Real-Time Polymerase Chain Reaction

Share to Receptors, Calcitriol

Source

Identifiers

PMID: 24320988
DOI: 10.1089/dna.2013.2217

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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