Article
Lack of association between the G-2548A polymorphism of the leptin gene and psoriasis in a Turkish population.
International journal of dermatology - 1 Dec 2007
Kara Nurten, Aydin Fatma, Senturk Nilgün, Gunes Sezgin, Canturk M Tayyar, Bagci Hasan, Bek Yüksel, Turanli Ahmet Yasar
Abstract excerpt
BACKGROUND: Psoriasis is a multifactorial disease in which genetic and inflammatory factors play important roles. Leptin is classified as a cytokine and plays an important role in the regulation of the T-helper response. A common polymorphism in the promoter of the human leptin gene (G-2548A) may...
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