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Article

Analysis of genetic variants of class II cytokine and their receptor genes in psoriasis patients of two ethnic groups from the Volga-Ural region of Russia.

Journal of dermatological science - 1 Oct 2012

Galimova Elvira, Akhmetova Vita, Latipov Boris, Kingo Külli, Rätsep Ranno, Traks Tanel, Kõks Sulev, Khusnutdinova Elza

Abstract excerpt

BACKGROUND: The molecular basis of pathogenesis of psoriasis remains unclear, but one unifying hypothesis of disease aetiology is the cytokine network model. The class II cytokines (CF2) and their receptors (CRF2) are all involved in the inflammatory processes and single nucleotide polymorphisms (SNPs) in respective genes have been associated with psoriasis in a previous study of the Estonian population....

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PMID: 22840887
DOI: 10.1016/j.jdermsci.2012.07.002

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