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Vitamin D receptor gene polymorphisms are associated with psoriasis susceptibility and the clinical response to calcipotriol in psoriatic patients.

Experimental dermatology - 1 Dec 2020

Liu Junlin, Wang Wei, Liu Kun, Wan Duoyan, Wu Zhiming, Cao Zhirui, Luo Yang, Xiao Chuanliu, Yin Mei

Abstract excerpt

Psoriasis is a common genetic disease characterized by hyperproliferation and disordered maturation of keratinocytes. To date, many association studies between psoriasis and VDR gene have been conducted, but the results are controversial. Furthermore, vitamin D3 analogue has anti-psoriatic activity; however, the clinical response is variable. This study was conducted to explore whether VDR gene polymorphisms are...

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PMID: 32997398
DOI: 10.1111/exd.14202

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