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Article

Association of GSTT1 polymorphism with acute myeloid leukemia risk is dependent on smoking status.

Leukemia & lymphoma - 1 Apr 2012

Kim Hee Nam, Kim Nan Young, Yu Li, Tran Huong Thi Thanh, Kim Yeo-Kyeoung, Lee Il-Kwon, Shin Min-Ho, Park Kyeong-Soo, Choi Jin-Su, Kim Hyeoung-Joon

Abstract excerpt

Genetic polymorphisms in drug-metabolizing, DNA repair and multidrug resistance genes affect the risks for many cancers. We analyzed 21 polymorphisms in 17 genes in these pathways to evaluate their association with the risk of acute myeloid leukemia (AML) and to examine whether smoking modifies these associations in a population-based study in Korea (415 cases, 1700 controls). We found marginal associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21942242
DOI: 10.3109/10428194.2011.625576

Genes

ERCC1
GSTT1
WRN
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of GSTT1 polymorphism with acute myeloid leukemia risk is dependent on smoking status.PMID 21942242Read ↗

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