Article
Overproduction of the yeast STE12 protein leads to constitutive transcriptional induction.
Genes & development - 1 Apr 1990
Dolan J W, Fields S
Abstract excerpt
Haploid a and alpha cells of the yeast Saccharomyces cerevisiae respond to the pheromones alpha- and a-factor, respectively, by increasing transcription of inducible genes, arresting cell division, and forming cell-surface projections. These responses are dependent on the activity of several genes, including STE12, whose product binds to the pheromone response element located within the regulatory DNA sequences...
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