Article
Receptor inhibition of pheromone signaling is mediated by the Ste4p Gbeta subunit.
Molecular and cellular biology - 1 Jan 1999
Kim J, Couve A, Hirsch J P
Abstract excerpt
The pheromone response pathway of the yeast Saccharomyces cerevisiae is initiated in MATa cells by binding of alpha-factor to the alpha-factor receptor. MATa cells in which the a-factor receptor is inappropriately expressed exhibit reduced pheromone signaling, a phenomenon termed receptor inhibit...
Topics
- Amino Acid Sequence
- Fungal Proteins
- GTP-Binding Protein alpha Subunits
- GTP-Binding Protein alpha Subunits, Gq-G11
- GTP-Binding Protein beta Subunits
- GTP-Binding Proteins
- Heterotrimeric GTP-Binding Proteins
- Molecular Sequence Data
- Mutagenesis
- Phenotype
- Pheromones
- Receptors, Mating Factor
- Receptors, Peptide
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Signal Transduction
- Transcription Factors
- Transcriptional Activation