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Article

Evidence for Epigenetic Abnormalities of the Androgen Receptor Gene in Foreskin from Children with Hypospadias

22 Sept 2011

Abstract excerpt

CONTEXT: Hypospadias is a malformation of the penis due to an incomplete development of the male urethra, the exact etiology of which in the majority of cases remains unknown. OBJECTIVE: The objective of the study was to assess whether defects of the androgen receptor (AR) gene (CAG repeats and methylation pattern) and DNA methyltransferases (DNMT) family are present in hypospadic patients. DESIGN: CAG repeats...

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Identifiers

PMID: 21937623
DOI: 10.1210/jc.2011-0511

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Evidence for Epigenetic Abnormalities of the Androgen Receptor Gene in Foreskin from Children with HypospadiasPMID 21937623Read ↗

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